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The general linear model or general multivariate regression model is a compact way of simultaneously writing several multiple linear regression models. In that sense it is not a separate statistical linear model. The various multiple linear regression models may be compactly written as [1]
The design matrix has dimension n-by-p, where n is the number of samples observed, and p is the number of variables measured in all samples. [4] [5]In this representation different rows typically represent different repetitions of an experiment, while columns represent different types of data (say, the results from particular probes).
Procedures for method evaluation and method comparison include ROC curve analysis, [6] Bland–Altman plot, [7] as well as Deming and Passing–Bablok regression. [ 8 ] The software also includes reference interval estimation, [ 9 ] meta-analysis and sample size calculations.
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Linear Template Fit (LTF) [7] combines a linear regression with (generalized) least squares in order to determine the best estimator. The Linear Template Fit addresses the frequent issue, when the residuals cannot be expressed analytically or are too time consuming to be evaluate repeatedly, as it is often the case in iterative minimization ...
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Consider a set of data points, (,), (,), …, (,), and a curve (model function) ^ = (,), that in addition to the variable also depends on parameters, = (,, …,), with . It is desired to find the vector of parameters such that the curve fits best the given data in the least squares sense, that is, the sum of squares = = is minimized, where the residuals (in-sample prediction errors) r i are ...