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From 1996 to 2012, under the trade name Lipitor, atorvastatin became the world's best-selling medication of all time, with more than $125 billion in sales over approximately 14.5 years. [ 116 ] and $13 billion a year at its peak, [ 117 ] Lipitor alone "provided up to a quarter of Pfizer Inc.'s annual revenue for years."
Statins are a type of medication that help lower low-density lipoprotein (LDL) cholesterol — or “bad” cholesterol — in the body. This helps keep the arteries clear so blood has an easier ...
Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood (hyperlipidemia). The American Heart Association recommends the descriptor ...
On average, statins can lower LDL cholesterol by 1.8 mmol/L (70 mg/dL), which translates into an estimated 60% decrease in the number of cardiac events (heart attack, sudden cardiac death) and a 17% reduced risk of stroke after long-term treatment. [36] A greater benefit is observed with high-intensity statin therapy. [37]
A recent study by the National Center for Health Statistics revealed that a higher percentage of women 20 and older have high total cholesterol than men in the same age group, and the rates ...
Cholesterol is a waxy, fat-like substance in the blood produced by the liver and from the food we eat. There are two kinds: low-density lipoprotein or LDL, the “bad” cholesterol, and high ...
A new way of determining heart disease risk may result in millions fewer people getting prescriptions for statins, ... such as kidney disease, obesity and a marker of poor blood sugar control ...
[1] [10] What people eat can also have an influence, with excessive alcohol use, too much carbohydrates, and diets high in saturated fats having a higher risk. [1] Some medications that may contribute to dyslipidemia are thiazide diuretics , beta blockers , oral contraceptives , atypical antipsychotics (clozapine, olanzapine), corticosteroids ...