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Levetiracetam, sold under the brand name Keppra among others, is a novel antiepileptic drug [7] used to treat epilepsy. [8] It is used for partial-onset , myoclonic , or tonic–clonic seizures, [ 7 ] and is taken either by mouth as an immediate or extended release formulation or by injection into a vein .
Hepatotoxicity may manifest as triglyceride accumulation, which leads to either small-droplet (microvesicular) or large-droplet (macrovesicular) fatty liver. There is a separate type of steatosis by which phospholipid accumulation leads to a pattern similar to the diseases with inherited phospholipid metabolism defects (e.g., Tay–Sachs disease )
FNH is found in 0.2%– 0.3% of adults worldwide. [2] FNH is more common in females (10:1 female to male ratio) except in Japan and China, in which there is a more equal prevalence of cases between females and males. [2] FNH is associated with women of childbearing years and has been associated with women taking hormonal oral contraceptives. [2]
Furthermore, the researchers estimated that 15.6 million U.S. adults have taken at least one herbal supplement in the last 30 days that might be hepatotoxic or damaging to their liver.
For the study, published in JAMA Network Open, researchers analyzed data from more than 9,500 American adults with an average age of 47.5 who participated in the National Health and Nutrition ...
When applied to the whole U.S. population, this percentage translates to about 15.6 million adults. This potentially hepatotoxic botanical use, researchers say, is similar to the estimated number ...
The first anticonvulsant was bromide, suggested in 1857 by the British gynecologist Charles Locock who used it to treat women with "hysterical epilepsy" (probably catamenial epilepsy). Bromides are effective against epilepsy, and also cause impotence, which is not related to its anti-epileptic effects. Bromide also suffered from the way it ...
Liver disease, or hepatic disease, is any of many diseases of the liver. [1] If long-lasting it is termed chronic liver disease . [ 3 ] Although the diseases differ in detail, liver diseases often have features in common.