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[citation needed] It is thought ASD is caused by the failure to close the hole (foramen ovale) between the right and left atrium normally found within the heart during fetal development; the creation of a hole between the atrium may also be acquired. There are two types of ASD: Ostium secundum and ASD Primum. [citation needed]
The ostium primum atrial septal defect is a defect in the atrial septum at the level of the tricuspid and mitral valves. This is sometimes known as an endocardial cushion defect because it often involves the endocardial cushion, which is the portion of the heart where the atrial septum meets the ventricular septum and the mitral valve meets the tricuspid valve.
An atrial septal defect is a congenital heart defect where the septum between the right and left atrium doesn’t close up all the way and remains open after birth. This causes oxygenated blood to go into pulmonary circulation. One complication from this condition is a paradoxical embolus which crosses from the right to the left side via the ASD.
Failure of the septum primum to fuse with the endocardial cushion can lead to an ostium primum atrial septal defect. [1] This is the second most common type of atrial septal defect [2] and is commonly seen in Down syndrome. Typically this defect will cause a shunt to occur from the left atrium to the right atrium.
An Atrial septal defect is a relatively common heart malformation that occurs when the interatrial septum fails to develop properly. Persistence of the ostium secundum is the most common atrial septal defect. [3] Additionally, in a subset of the population, the foramen ovale is not overtly patent but the two septa have not fused.
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