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2. How to treat foot calluses, according to experts - AOL

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   The best way to treat and prevent foot calluses involves at least three steps, according to our experts: physically exfoliate to remove dead skin, use a topical cream to further exfoliate and ...

3. Callus - Wikipedia

   en.wikipedia.org/wiki/Callus

   A callus (pl.: calluses) is an area of thickened and sometimes hardened skin that forms as a response to repeated friction, pressure, or other irritation. Since repeated contact is required, calluses are most often found on the feet and hands, but they may occur anywhere on the skin. Some degree of callus, such as on the bottom of the foot, is ...

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5. Urea-containing cream - Wikipedia

   en.wikipedia.org/wiki/Urea-containing_cream

   Urea cream is indicated for debridement and promotion of normal healing of skin areas with hyperkeratosis, particularly where healing is inhibited by local skin infection, skin necrosis, fibrinous or itching debris or eschar. [5] Specific condition with hyperkeratosis where urea cream is useful include: Dry skin and rough skin [5] Dermatitis [5]

6. Bone healing - Wikipedia

   en.wikipedia.org/wiki/Bone_healing

   Stromal cell-derived factor 1 (SDF-1) and CXCR4 mediate recruitment of mesenchymal stem cells. IL-1 and IL-6 are the most important cytokines for bone healing. IL-1 promotes formation of callus and of blood vessels. IL-6 promotes differentiation of osteoblasts and osteoclasts. [4] All cells within the blood clot degenerate and die.

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