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Micrograph showing contraction band necrosis, a histopathologic finding of myocardial infarction (heart attack). Histopathology (compound of three Greek words: ἱστός histos 'tissue', πάθος pathos 'suffering', and -λογία-logia 'study of') is the microscopic examination of tissue in order to study the manifestations of disease.
An incisional biopsy or core biopsy samples a portion of the abnormal tissue without attempting to remove the entire lesion or tumor. When a sample of tissue or fluid is removed with a needle in such a way that cells are removed without preserving the histological architecture of the tissue cells, the procedure is called a needle aspiration ...
Fibrinoid necrosis is a pathological lesion that affects blood vessels, and is characterized by the occurrence of endothelial damage, followed by leakage of plasma proteins, including fibrinogen, from the vessel lumen; these proteins infiltrate and deposit within the vessel walls, where fibrin polymerization subsequently ensues.
A papillary fibroelastoma is a primary tumor of the heart that typically involves one of the heart valves. [1] Papillary fibroelastomas, while considered uncommon, make up about 10 percent of all primary tumors of the heart. [2] They are the third most common type of primary tumor of the heart, [3] behind cardiac myxomas and cardiac lipomas.
Molecular pathology is focused upon the study and diagnosis of disease through the examination of molecules within organs, tissues or bodily fluids. [21] Molecular pathology is multidisciplinary by nature and shares some aspects of practice with both anatomic pathology and clinical pathology, molecular biology, biochemistry, proteomics and ...
Surgical pathology is the most significant and time-consuming area of practice for most anatomical pathologists. Surgical pathology involves gross and microscopic examination of surgical specimens, as well as biopsies submitted by surgeons and non- surgeons such as general internists , medical subspecialists, dermatologists , and interventional ...
Cardiac catheterization and biopsy: In this procedure, a catheter is inserted into the groin and threaded through the blood vessels to the heart, where a biopsy of the heart can be extracted for laboratory analysis. [15] Autopsy: Cardiomegaly is indicated if the heart weighs more than >399 grams in women and >449 grams in men. [28]
It is much more common to find metastasis from an alternate site than a primary heart tumor. [7] However, primary cardiac tumors do occur. One of these is the cardiac rhabdomyoma. Approximately 80-90% of these tumors are found in patients with tuberous sclerosis, a genetic condition causing multiple tumors, with most found prior to the age of ...