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  2. Committed step - Wikipedia

    en.wikipedia.org/wiki/Committed_step

    In this scheme, enzyme c catalyzes the committed step in the biosynthesis of compound 6. In biochemistry , the committed step (also known as the first committed step ) is an effectively irreversible , enzyme - catalyzed reaction that occurs at a branch point during the biosynthesis of some molecules .

  3. Amphibolic - Wikipedia

    en.wikipedia.org/wiki/Amphibolic

    The pathway uses a different enzyme for each direction for the irreversible step in the pathway, allowing independent regulation of catabolism and anabolism. Due their inherent duality, amphibolic pathways represent the regulation modes of both anabolic by its negative feedback end product and catabolic by feedback by energy indicator sequences.

  4. Pyruvate kinase - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_kinase

    This final step is highly regulated and deliberately irreversible because pyruvate is a crucial intermediate building block for further metabolic pathways. [17] Once pyruvate is produced, it either enters the TCA cycle for further production of ATP under aerobic conditions, or is converted to lactic acid or ethanol under anaerobic conditions.

  5. Metabolic pathway - Wikipedia

    en.wikipedia.org/wiki/Metabolic_pathway

    [5]: 572 To the right is an illustration of the amphibolic properties of the TCA cycle. The glyoxylate shunt pathway is an alternative to the tricarboxylic acid (TCA) cycle, for it redirects the pathway of TCA to prevent full oxidation of carbon compounds, and to preserve high energy carbon sources as future energy sources. This pathway occurs ...

  6. Citric acid cycle - Wikipedia

    en.wikipedia.org/wiki/Citric_acid_cycle

    Overview of the citric acid cycle. The citric acid cycle—also known as the Krebs cycle, Szent–Györgyi–Krebs cycle, or TCA cycle (tricarboxylic acid cycle) [1] [2] —is a series of biochemical reactions to release the energy stored in nutrients through the oxidation of acetyl-CoA derived from carbohydrates, fats, proteins, and alcohol.

  7. Reverse Krebs cycle - Wikipedia

    en.wikipedia.org/wiki/Reverse_Krebs_cycle

    The Reductive/Reverse TCA Cycle (rTCA cycle). Shown are all of the reactants, intermediates and products for this cycle. The reverse Krebs cycle (also known as the reverse tricarboxylic acid cycle, the reverse TCA cycle, or the reverse citric acid cycle, or the reductive tricarboxylic acid cycle, or the reductive TCA cycle) is a sequence of chemical reactions that are used by some bacteria and ...

  8. Police regain the eastern steps of the U.S. Capitol building as protests as the U.S. Congress meets to formally ratify Joe Biden as the winner of the 2020 Presidential election on Jan. 6, 2021.

  9. Glycolysis - Wikipedia

    en.wikipedia.org/wiki/Glycolysis

    Phosphofructokinase is an important control point in the glycolytic pathway, since it is one of the irreversible steps and has key allosteric effectors, AMP and fructose 2,6-bisphosphate (F2,6BP). F2,6BP is a very potent activator of phosphofructokinase (PFK-1) that is synthesized when F6P is phosphorylated by a second phosphofructokinase ( PFK2 ).