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  2. Mouse models of breast cancer metastasis - Wikipedia

    en.wikipedia.org/wiki/Mouse_models_of_breast...

    MMTV-PyMT is the model of breast cancer metastasis, in which MMTV-LTR is used to drive the expression of mammary gland specific polyomavirus middle T-antigen, leading to a rapid development of highly metastatic tumors. [45] MMTV-PyMT is the most commonly used model for the study of mammary tumor progression and metastasis.

  3. Multiomics - Wikipedia

    en.wikipedia.org/wiki/Multiomics

    Number of citations of the terms "Multiomics" and "Multi-omics" in PubMed until the 31st December 2021. Multiomics, multi-omics, integrative omics, "panomics" or "pan-omics" is a biological analysis approach in which the data sets are multiple "omes", such as the genome, proteome, transcriptome, epigenome, metabolome, and microbiome (i.e., a meta-genome and/or meta-transcriptome, depending ...

  4. Time-resolved RNA sequencing - Wikipedia

    en.wikipedia.org/wiki/Time-resolved_RNA_sequencing

    Time-resolved RNA sequencing methods are applications of RNA-seq that allow for observations of RNA abundances over time in a biological sample or samples. Second-Generation DNA sequencing has enabled cost effective, high throughput and unbiased analysis of the transcriptome. [1]

  5. New blood test can spot breast cancer at earliest ... - AOL

    www.aol.com/blood-test-spot-breast-cancer...

    Standard tests for breast cancer involve a physical examination, X-ray, ultrasound scans, or an analysis of a sample of breast tissue known as a biopsy, with early detection strategies relying on ...

  6. Oncogenomics - Wikipedia

    en.wikipedia.org/wiki/Oncogenomics

    Oncogenomics is a sub-field of genomics that characterizes cancer-associated genes.It focuses on genomic, epigenomic and transcript alterations in cancer. Cancer is a genetic disease caused by accumulation of DNA mutations and epigenetic alterations leading to unrestrained cell proliferation and neoplasm formation.

  7. Cancer genome sequencing - Wikipedia

    en.wikipedia.org/wiki/Cancer_genome_sequencing

    The first report of cancer genome sequencing appeared in 2006. In this study 13,023 genes were sequenced in 11 breast and 11 colorectal tumors. [3] A subsequent follow up was published in 2007 where the same group added just over 5,000 more genes and almost 8,000 transcript species to complete the exomes of 11 breast and colorectal tumors. [4]

  8. Blood test ‘could detect breast cancer up to two ... - AOL

    www.aol.com/blood-test-could-detect-breast...

    An analysis of 30 blood samples – taken over time from three women who have been diagnosed with breast cancer and three women who have not – showed changes in the levels of a set of six proteins.

  9. 4T1 - Wikipedia

    en.wikipedia.org/wiki/4T1

    The 4T1 cell line is widely used as a syngeneic model for human triple-negative breast cancer, which is responsible for more than 17% of breast cancers diagnosed worldwide each year. [ 7 ] 4T1 cells can be transplanted into the fat pad of the murine mammary gland, where they are highly tumorigenic, invasive, and spontaneously metastasize to ...

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