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As globus sensation is a symptom, a diagnosis of globus pharyngis is typically a diagnosis of exclusion. If globus sensation is presenting with other symptoms such as pain, swallowing disorders such as aspiration or regurgitation (dysphagia), weight loss, or voice change, [ 10 ] an organic cause needs to be investigated, typically with endoscopy .
Laryngopharyngeal reflux (LPR) or laryngopharyngeal reflux disease (LPRD) is the retrograde flow of gastric contents into the larynx, oropharynx and/or the nasopharynx. [4] [5] LPR causes respiratory symptoms such as cough and wheezing [6] and is often associated with head and neck complaints such as dysphonia, globus pharyngis, and dysphagia. [7]
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Globus pharyngeus (feeling like there is a lump in the throat) Cold or flu-like symptoms (which, like a cough, may also be a causal factor for laryngitis) Swollen lymph nodes in the throat, chest, or face; Fever; General muscle pain ; Shortness of breath, predominantly in children
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