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As globus sensation is a symptom, a diagnosis of globus pharyngis is typically a diagnosis of exclusion. If globus sensation is presenting with other symptoms such as pain, swallowing disorders such as aspiration or regurgitation (dysphagia), weight loss, or voice change, [ 10 ] an organic cause needs to be investigated, typically with endoscopy .
Laryngopharyngeal reflux (LPR) or laryngopharyngeal reflux disease (LPRD) is the retrograde flow of gastric contents into the larynx, oropharynx and/or the nasopharynx. [4] [5] LPR causes respiratory symptoms such as cough and wheezing [6] and is often associated with head and neck complaints such as dysphonia, globus pharyngis, and dysphagia. [7]
They cause muscle tension on the cricoid cartilage, leading to a globus feeling. Pharyngeal spasms, a more common source of a globus feeling, cause tension on the thyroid cartilage. They move up and down, left and right in the pharyngeal muscles. Both may be present. The patient complains about the signs and symptoms enumerated above.
Dysphagia is distinguished from other symptoms including odynophagia, which is defined as painful swallowing, [8] and globus, which is the sensation of a lump in the throat. A person can have dysphagia without odynophagia (dysfunction without pain), odynophagia without dysphagia (pain without dysfunction) or both together.
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Developmental Editor: John Barstow Editorial Director: Shay Totten Project Manager: Emily Foote Copy Editor: Nancy Crompton Fact-checker: Mary Fratini Book Designer: Peter Holm Printed in Canada on recycled paper. First printing, July 2007 10 9 8 7 6 5 4 3 2 1 Library of Congress Cataloging-in-Publication Data Wolf, Naomi.
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