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  2. Lenalidomide - Wikipedia

    en.wikipedia.org/wiki/Lenalidomide

    Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone . [ 8 ]

  3. Cereblon E3 ligase modulator - Wikipedia

    en.wikipedia.org/wiki/Cereblon_E3_ligase_modulator

    The thalidomide molecule is a synthetic derivative of glutamic acid and consists of a glutarimide ring and a phthaloyl ring (Figure 5). [15] [16] Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione and it has one chiral center [15] After thalidomide's selective inhibition of TNF-α had been reported, a renewed effort was put in thalidomide's clinical development.

  4. Celgene - Wikipedia

    en.wikipedia.org/wiki/Celgene

    Celgene Corporation is a pharmaceutical company that makes cancer and immunology drugs. Its major product is Revlimid (lenalidomide), which is used in the treatment of multiple myeloma, and also in certain anemias.

  5. Celgene's Revlimid Faces a Tough Sell - AOL

    www.aol.com/2013/11/18/celgenes-revlimid-faces-a...

    When it comes to drug pricing, European regulators are a tough sell. Just ask Johnson & Johnson . The U.K.'s National Institute for Health and Care Excellence, or NICE, took a pass on paying for ...

  6. Novartis, Seattle Genetics, Celgene Reveal Latest News on ...

    www.aol.com/2010/12/06/novartis-seattle-genetics...

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  7. Novartis, Seattle Genetics, Celgene Reveal Latest News on ...

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  8. Pomalidomide - Wikipedia

    en.wikipedia.org/wiki/Pomalidomide

    In the European Union, pomalidomide, in combination with bortezomib and dexamethasone, is indicated in the treatment of adults with multiple myeloma who have received at least one prior treatment regimen including lenalidomide; [8] and in combination with dexamethasone is indicated in the treatment of adults with relapsed and refractory multiple myeloma who have received at least two prior ...

  9. Celgene's Bet on Epizyme Pays Off - AOL

    www.aol.com/news/2014-01-11-celgenes-bet-on...

    A healthy payment from big biotech Celgene Corporation helped Epizyme Inc. make one of the biggest moves in biotech so far this year. News that Epizyme Inc.'s EPZ-5676 met its proof of concept ...

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