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Ammocallis rosea (L.) Small (See also Synonyms section) Catharanthus roseus , commonly known as bright eyes , Cape periwinkle , graveyard plant , Madagascar periwinkle , old maid , pink periwinkle , rose periwinkle , [ 2 ] is a perennial species of flowering plant in the family Apocynaceae .
Catharanthus roseus, known formerly as Vinca rosea, is a main source of vinca alkaloids, now sometimes called catharanthus alkaloids. The plant produces about 130 of these compounds, including vinblastine and vincristine, two drugs used to treat cancer. [8] [9] [10] [11]
Vinca (/ ˈ v ɪ ŋ k ə /; [2] Latin: vincire "to bind, fetter") is an Old World genus of flowering plants in the family Apocynaceae, The English name periwinkle is shared with the related genus Catharanthus (and with the mollusc Littorina littorea). Some Vinca species are cultivated but have also spread invasively.
Vinca alkaloids are a set of anti-mitotic and anti-microtubule alkaloid agents originally derived from the periwinkle plant Catharanthus roseus (basionym Vinca rosea) and other vinca plants. They block beta-tubulin polymerization in a dividing cell.
Vinca may refer to: Vinca, one of two genera of plants with the common name Periwinkle; Catharanthus a genus of flowering plants, the species of which are commonly called, as with Vinca species, Periwinkle; Catharanthus roseus, an annual bedding plant, formerly included in the Vinca genus as Vinca rosea. It shares its common name Periwinkle ...
Special Herbs, Vols. 9 & 0 is an instrumental album released by MF Doom under the moniker Metal Fingers. As with all volumes of Special Herbs released by Metal Fingers, each track is named after a herb or similar flora (with the exception of "Untitled (Meditation)").
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The Vinca alkaloids bind to the β-subunit of tubulin dimers at a distinct region called the Vinca-binding domain. They bind to tubulin rapidly, and this binding is reversible and independent of temperature (between 0 °C and 37 °C). In contrast to colchicine, vinca alkaloids bind to the microtubule directly.
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