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Lateral meningocele syndrome, also known as Lehman syndrome, [2] is a very rare skeletal disorder with facial anomalies, hypotonia, and meningocele-related neurologic dysfunction. [3]
A lumbar myelomeningocele. Myelomeningocele (MMC), also known as meningomyelocele, is the type of spina bifida that often results in the most severe complications and affects the meninges and nerves. [30] In individuals with myelomeningocele, the unfused portion of the spinal column allows the spinal cord to protrude through an opening.
In neurology, a lipomyelomeningocele is a type of closed neural tube defect that affects around 3 to 6 babies out of 100,000 births. [1] [2] It is an example of a spinal lipoma, which is a collection of adipose tissue, or fat, that is located at or around the spinal cord.
The MOMS Trial was a clinical trial that studied treatment of a birth defect called myelomeningocele, which is the most severe form of spina bifida. The study looked at prenatal (before birth) and postnatal (after birth) surgery to repair this defect. The first major phase concluded that prenatal surgery had strong, long-term benefits and some ...
Neural tube defects (NTDs) are a group of birth defects in which an opening in the spine or cranium remains from early in human development. In the third week of pregnancy called gastrulation, specialized cells on the dorsal side of the embryo begin to change shape and form the neural tube.
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Encephalocele is a neural tube defect characterized by sac-like protrusions of the brain and the membranes that cover it through openings in the skull.These defects are caused by failure of the neural tube to close completely during fetal development.
premature aging features with shorter life span and photosensitivity, [14] deficient transcription coupled NER with accumulation of unrepaired DNA damages, [15] also defective repair of oxidatively generated DNA damages including 8-oxoguanine, 5-hydroxycytosine and cyclopurines [15] ERCC8 (Cockayne syndrome A or CS-A)