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Upon heating, salicylic acid converts to phenyl salicylate: [27] [8] 2 HOC 6 H 4 CO 2 H → C 6 H 5 O 2 C 6 H 4 OH + CO 2 + H 2 O. Further heating gives xanthone. [8] Salicylic acid as its conjugate base is a chelating agent, with an affinity for iron(III). [28] Salicylic acid slowly degrades to phenol and carbon dioxide at 200–230 °C: [29]
It does so by acetylating the hydroxyl of a serine residue at the 530 amino acid position. [6] Normally COX produces prostaglandins, most of which are pro-inflammatory, and thromboxanes, which promote clotting. Aspirin-modified COX-2 produces 15-epi-lipoxins, which act to resolve inflammatory responses similar to other lipoxins. [7]
Aspirin is the genericized trademark for acetylsalicylic acid (ASA), a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and inflammation, and as an antithrombotic. [10] Specific inflammatory conditions that aspirin is used to treat include Kawasaki disease , pericarditis , and rheumatic fever .
Salicylic acid is a topical skincare ingredient used to treat conditions, like acne, warts, and psoriasis. ... Psoriasis is an auto-immune disease that causes inflammation. In its most common form ...
Dr. Garshick also recommends anti-dandruff shampoos if the scabs are developing from seborrheic dermatitis, and says to look for ketoconazole or salicylic acid in the ingredients, such as Nizoral ...
Salicylic acid cleansers reduce oil, wash away impurities, and fight acne, leaving you with smooth skin. Dermatologists share their top picks here. ... This natural cleanser “fights inflammation ...
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