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The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts.
Homeobox genes encode homeodomain protein products that are transcription factors sharing a characteristic protein fold structure that binds DNA to regulate expression of target genes. [ 3 ] [ 4 ] [ 2 ] Homeodomain proteins regulate gene expression and cell differentiation during early embryonic development, thus mutations in homeobox genes can ...
Starvation ensues when the fat reserves are completely exhausted and protein is the only fuel source available to the body. Thus, after periods of starvation, the loss of body protein affects the function of important organs, and death results, even if there are still fat reserves left unused.
One cup of low-fat milk has 8 grams of protein and 100 calories, while Greek yogurt provides 15 grams of protein in a small 5.3-ounce container. As for cottage cheese, half a cup has about 12 ...
The daily recommended amount of calories per day is 2,000 for women and 2,500 for men. Calories provide the energy needed to stay alive, but some foods pack in more "empty" calories, i.e. those ...
The POU domain is a bipartite domain composed of two subunits separated by a non-conserved region of 15-55 aa. The N-terminal subunit is known as the POU-specific (POUs) domain (InterPro: IPR000327), while the C-terminal subunit is a homeobox domain (InterPro: IPR007103). 3D structures of complexes including both POU subdomains bound to DNA are available.
18091 Ensembl ENSG00000183072 ENSMUSG00000015579 UniProt P52952 P42582 RefSeq (mRNA) NM_004387 NM_001166175 NM_001166176 NM_008700 RefSeq (protein) NP_001159647 NP_001159648 NP_004378 NP_032726 Location (UCSC) Chr 5: 173.23 – 173.24 Mb Chr 17: 27.06 – 27.06 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Nkx-2.5 is a protein that in humans is encoded by the NKX2 ...
Research backs this up: Young men who consumed more protein while losing weight and on an intense exercise regiment gained about 2.5 pounds of muscle, while the young men who consumed less protein ...