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In the brain, serotonin is a neurotransmitter and regulates arousal, behavior, sleep, and mood, among other things. [9] During prolonged exercise where central nervous system fatigue is present, serotonin levels in the brain are higher than normal physiological conditions; these higher levels can increase perceptions of effort and peripheral muscle fatigue. [9]
Causes Narcolepsy , idiopathic hypersomnia , circadian rhythm sleep disorder , sleep apnea , others Excessive daytime sleepiness ( EDS ) is characterized by persistent sleepiness and often a general lack of energy, even during the day after apparently adequate or even prolonged nighttime sleep.
Fatigue is a state of tiredness (which is not sleepiness), exhaustion [1] or loss of energy. [2] [3]Fatigue (in the medical sense) is sometimes associated with medical conditions including autoimmune disease, organ failure, chronic pain conditions, mood disorders, heart disease, infectious diseases, and post-infectious-disease states. [4]
According to one Centers for Disease Control and Prevention (CDC) study, among 74,571 adult respondents in 12 U.S. states, 35.3% reported <7 hours of sleep during a typical 24-hour period, 48.0% reported snoring, 37.9% reported unintentionally falling asleep during the day at least once in the preceding month, and 4.7% reported nodding off or ...
Additionally, fatigue must persist for at least six months, substantially impair activities in all areas of life, and have a clearly defined onset. [ 10 ] : 16–17 Symptoms must be present at least half of the time, and be of moderate severity or worse; previous criteria just required symptoms to be present.
The onset of directed attention fatigue can be triggered by a number of activities involving the use of the brain's inhibitory system. Activities that engage this system include multitasking, [ 7 ] working in an environment with disruptive background noise, [ citation needed ] a lack of sleep, [ 8 ] and rapidly changing focus during a prolonged ...
Other symptoms that may occur during PEM include cognitive impairment, flu-like symptoms, pain, weakness, and trouble sleeping. [6] [4] Though typically cast as a worsening of existing symptoms, patients may experience some symptoms exclusively during PEM. [6] Patients often describe PEM as a "crash", "relapse", or "setback". [6]
Openclipart, also called Open Clip Art Library, is an online media repository of free-content vector clip art.The project hosts over 160,000 free graphics and has billed itself as "the largest community of artists making the best free original clipart for you to use for absolutely any reason".