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  2. XY sex-determination system - Wikipedia

    en.wikipedia.org/wiki/XY_sex-determination_system

    The idea is instead of having a simplistic mechanism by which you have pro-male genes going all the way to make a male, in fact there is a solid balance between pro-male genes and anti-male genes and if there is a little too much of anti-male genes, there may be a female born and if there is a little too much of pro-male genes then there will ...

  3. Sex-determination system - Wikipedia

    en.wikipedia.org/wiki/Sex-determination_system

    In birds, the genes FET1 and ASW are found on the W chromosome for females, similar to how the Y chromosome contains SRY. [9] However, not all species depend upon the W for their sex. For example, there are moths and butterflies that are ZW, but some have been found female with ZO, as well as female with ZZW. [ 22 ]

  4. Sexual differentiation in humans - Wikipedia

    en.wikipedia.org/wiki/Sexual_differentiation_in...

    The human Y chromosome showing the SRY gene which codes for a protein regulating sexual differentiation. Sexual differentiation in humans is the process of development of sex differences in humans . It is defined as the development of phenotypic structures consequent to the action of hormones produced following gonadal determination. [ 1 ]

  5. Major histocompatibility complex and sexual selection

    en.wikipedia.org/wiki/Major_histocompatibility...

    These genes have maintained an unusually high level of allelic diversity throughout time and throughout different populations. This means that for each MHC gene, many alleles (or gene variants) consistently exist within the population, and many individuals are heterozygous at MHC loci (meaning they possess two different alleles for a given gene ...

  6. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA. Homozygous describes a genotype consisting of two identical alleles at a given locus, heterozygous describes a genotype consisting of two different alleles at a locus, hemizygous describes a genotype consisting of only a single copy of a particular gene in an ...

  7. Sex differences in human physiology - Wikipedia

    en.wikipedia.org/wiki/Sex_differences_in_human...

    The X-chromosome carries a larger number of genes in comparison to the Y-chromosome. In humans, X-chromosome inactivation enables males and females to have an equal expression of the genes on the X-chromosome since females have two X-chromosomes while males have a single X and a Y chromosome. X-chromosome inactivation is random in the somatic ...

  8. Fabry disease - Wikipedia

    en.wikipedia.org/wiki/Fabry_disease

    At least 443 disease-causing mutations in the GLA gene have been discovered. [12] The DNA mutations that cause the disease are X-linked recessive with incomplete penetrance in heterozygous females. The condition affects hemizygous males (i.e. all non-intersex males), as well as homozygous, and in many cases heterozygous females.

  9. Sexual differentiation - Wikipedia

    en.wikipedia.org/wiki/Sexual_differentiation

    Sexual differentiation is the process of development of the sex differences between males and females from an undifferentiated zygote. [1] [2] Sex determination is often distinct from sex differentiation; sex determination is the designation for the development stage towards either male or female, while sex differentiation is the pathway towards the development of the phenotype.