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This condition was formerly referred to as manic depression. People with bipolar disorder may experience rapid cycling between these abnormal mood states. ... Cariprazine (Vraylar®) Lurasidone ...
Cariprazine, sold under the brand name Vraylar among others, is an atypical antipsychotic developed by Gedeon Richter, [8] which is used in the treatment of schizophrenia, bipolar mania, [9] bipolar depression, [10] and major depressive disorder. [6] It acts primarily as a D 3 and D 2 receptor partial agonist, with a preference for the D 3 ...
Lurasidone, sold under the brand name Latuda among others, is an antipsychotic medication used to treat schizophrenia and bipolar depression. [2] It is taken by mouth.. Common side effects include nausea, mild movement problems, sedation, and restlessness. [2]
Aripiprazole, brexpiprazole, cariprazine, olanzapine, and quetiapine have been approved as adjunct treatment for MDD by the FDA in the United States. [43] [44] Cariprazine, Quetiapine, lurasidone, and lumateperone [45] have been approved, as monotherapies, for bipolar depression, but as of present, lurasidone has not been approved for MDD. [43]
At least five atypical antipsychotics (lumateperone, [48] cariprazine, [49] lurasidone, [50] olanzapine, [51] and quetiapine [52]) have also been found to possess efficacy in the treatment of bipolar depression as a monotherapy, whereas only olanzapine [53] and quetiapine [54] [55] have been proven to be effective broad-spectrum (i.e., against ...
A variety of other agents have been tried in bipolar disorder, including benzodiazepines, calcium channel blockers, L-methylfolate, and thyroid hormone. [2] Modafinil (Provigil) and pramipexole (Mirapex) have been suggested for treating cognitive dysfunction associated with bipolar depression, but evidence supporting their use is quite limited.
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