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The infectious agent is a misfolded form of a host-encoded protein called prion (PrP). Prion proteins are encoded by the Prion Protein Gene . [22] The two forms of prion are designated as PrP c, which is a normally folded protein, and PrP sc, a misfolded form which gives rise to the disease.
A normal laugh has the structure of "ha-ha-ha" or "ho-ho-ho". It is unnatural, and one is physically unable, to have a laugh structure of "ha-ho-ha-ho". The usual variations of a laugh most often occur in the first or final note in a sequence- therefore, "ho-ha-ha" or "ha-ha-ho" laughs are possible.
Humour (Commonwealth English) or humor (American English) is the tendency of experiences to provoke laughter and provide amusement.The term derives from the humoral medicine of the ancient Greeks, which taught that the balance of fluids in the human body, known as humours (Latin: humor, "body fluid"), controlled human health and emotion.
Gelotology was first studied by psychiatrists, although some doctors in antiquity recommended laughter as a form of medicine. It was initially deprecated by most other physicians, who doubted that laughter possessed analgesic qualities.
The Tanganyika laughter epidemic of 1962 was an outbreak of mass hysteria—or mass psychogenic illness (MPI)—rumored to have occurred in or near the village of Kashasha on the western coast of Lake Victoria in Tanganyika (which, once united with Zanzibar, became the modern nation of Tanzania) near the border with Uganda.
Matthew Tenedorio, 25, who died in the attack, has been remembered by his family as "a beloved son, brother, uncle, and friend whose laid-back spirit and infectious laughter brought joy to ...
A simple smiley. This is a list of emoticons or textual portrayals of a writer's moods or facial expressions in the form of icons.Originally, these icons consisted of ASCII art, and later, Shift JIS art and Unicode art.
Detail of the Mona Lisa, who is known for her smile. A smiling child. A smile is a facial expression formed primarily by flexing the muscles at the sides of the mouth.Some smiles include a contraction of the muscles at the corner of the eyes, an action known as a Duchenne smile.