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Thyroiditis is generally caused by an immune system attack on the thyroid, resulting in inflammation and damage to the thyroid cells. This disease is often considered a malfunction of the immune system and can be associated with IgG4-related systemic disease, in which symptoms of autoimmune pancreatitis, retroperitoneal fibrosis and noninfectious aortitis also occur.
Acute infectious thyroiditis (AIT) also known as suppurative thyroiditis, microbial inflammatory thyroiditis, pyrogenic thyroiditis and bacterial thyroiditis. [ 1 ] [ 2 ] [ 3 ] The thyroid is normally very resistant to infection.
Long-term mild excess of thyroid hormone can thus cause impaired cardiac reserve and exercise capacity. [4] In a large population-based study of 2008, the odds of having poorer cognitive function were greater for sub-clinical hyperthyroidism than for stroke , diabetes mellitus , and Parkinson's disease . [ 48 ]
Postpartum thyroiditis can recur in subsequent pregnancies. [2] [4] [5] Drug-induced thyroiditis can occur in individuals receiving certain therapies such as amiodarone, interferon-alpha, lithium, tyrosine-kinase inhibitors, and immunotherapies among other drugs. These individuals may develop subacute lymphocytic thyroiditis. [2] [3] [4] [5]
The accuracy of the diagnosis depends on obtaining tissue from all of the suspicious areas of an abnormal thyroid gland. The reliability of fine needle aspiration is increased when sampling can be guided by ultrasound, and over the last 15 years, this has become the preferred method for thyroid biopsy in North America. [32] [citation needed]
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De Quervain's thyroiditis, also known as subacute granulomatous thyroiditis or giant cell thyroiditis, is a self-limiting inflammatory illness of the thyroid gland. [1] De Quervain thyroiditis is characterized by fever , flu-like symptoms , a painful goiter , and neck pain .
It is unknown why males are predominantly affected, with rates in males being 17- to 70-fold those in females, despite thyroid overactivity being much more common in women. [ 1 ] [ 2 ] History