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7-Hydroxycannabidiol (7-OH-CBD) is an active metabolite of cannabidiol, generated in the body from cannabidiol by the action of the enzyme CYP2C19. [1] While methods have been developed for its synthetic production, [2] and measurement of levels in the body following consumption of cannabidiol, [3] its pharmacology has been relatively little studied, though it has been found to possess similar ...
[23] [24] It may be supplied as CBD oil containing only CBD as the active ingredient (excluding THC or terpenes), CBD-dominant hemp extract oil, capsules, dried cannabis, or prescription liquid solution. [4] [20] CBD does not have the same psychoactivity as THC, [25] [26] and can modulate the psychoactive effects of THC on the body if both are ...
CBD is hydroxylated by P450 liver enzymes into 7-OH-CBD. Its metabolites are products of primarily CYP2C19 and CYP3A4 activity, with potential activity of CYP1A1, CYP1A2, CYP2C9, and CYP2D6. [69] Similar to delta-9-THC, a majority of CBD is excreted in feces and some in the urine. [57] The terminal half-life is approximately 18–32 hours. [70]
Unlike CBD oil and CBD tincture, CBD capsules offer a standard dose of cannabidiol without the hassle of calculating or measuring. “There’s a lot of control over the product and it’s easy ...
CBD shares a precursor with THC and is the main cannabinoid in CBD-dominant Cannabis strains. CBD has been shown to play a role in preventing the short-term memory loss associated with THC. [29] There is tentative evidence that CBD has an anti-psychotic effect, but research in this area is limited. [30] [24]
These CBD gummies from CBDfx combine the detox health benefits of apple cider vinegar with 50mg of broad-spectrum CBD to aid in relaxation and ease everyday aches and pains.
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Most commonly, gummy supplements are made from gelatin, cornstarch, water and sugar, along with flavorings. [7]Although gummy vitamins are the most popular type of gummy supplements, they may also be derived from herbal supplements, containing extracts from plants like ashwagandha [8] and cannabis (e.g., CBD), [9] as well as the algae-derived astaxanthin.