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The mechanism that produces the purported hallucinogenic and entheogenic effects of 5-MeO-DiPT is thought to result primarily from 5-HT 2A receptor agonism, although additional mechanisms of action such as monoamine oxidase inhibition (MAOI) may be involved also. [3] The strongest receptor binding affinity for 5-MeO-DiPT is at the 5-HT 1A ...
Little is known about the subjective effects of 5-MeO-DPT, but the nature of the compound is probably comparable to 5-MeO-DiPT, 5-MeO-DMT, or DPT, which are also psychedelic tryptamines/indoles. However, the duration of the above-mentioned drugs vary considerably.
The following is a list of psychedelic drugs of various chemical classes, including both naturally occurring and synthetic compounds. Serotonergic psychedelics are usually considered the "classical" psychedelics [dubious – discuss], whereas the other classes are often seen as having only secondary psychedelic properties; nonetheless all of the compounds listed here are considered ...
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5-Methoxy-N-propyl-N-isopropyltryptamine (5-MeO-PiPT) is a substituted tryptamine derivative which is claimed to have psychedelic effects. It acts as a 5-HT 1A and 5-HT 2A receptor agonist, [ 1 ] with an EC 50 of 13.8 nM and an efficacy of 89% (vs 5-HT), [ 2 ] and has been sold as a designer drug , first being identified in 2021 in British ...
5,N-Dimethyl-N-isopropyltryptamine (5-Me-MiPT) is a tryptamine derivative that is thought to be a psychedelic drug.It was first made in 1989. In vitro binding experiments on brain homogenates showed it to have serotonin receptor binding affinity between that of MiPT and 5-MeO-MiPT, [1] both of which are known to be active psychedelics in humans.
5-MeO-DBT (5-Methoxy-N,N-dibutyltryptamine, 5-MeO-BET) is a rare substituted tryptamine derivative, which is thought to be a psychoactive substance and was identified in a designer drug sample by a forensic laboratory in Slovenia in March 2021, [1] although only analytical studies have been conducted and no pharmacological data is available.
The widespread recreational use of N,N-dialkylated 5-methoxytryptamine derivatives including 5-MeO-DMT, 5-MeO-MiPT and 5-MeO-DiPT has led to concern that the 5-ethoxy homologs of these drugs could emerge as novel designer drugs, and consequently 5-EtO-DMT and other derivatives including 5-EtO-DET, 5-EtO-DPT, 5-EtO-DiPT, 5-EtO-DALT, 5-EtO-MPT, 5 ...