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Too much sugar, especially that which is highly processed, is associated with multiple adverse health risks. For example, childhood obesity rates have tripled in the last 30 years.
As any parent who's taken their child to a birthday party knows, a single bite of cake can appear to send your kid's energy levels into overdrive.
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In untreated hyperglycemia, a condition called ketoacidosis may develop because decreased insulin levels increase the activity of hormone sensitive lipase. [21] The degradation of triacylglycerides by hormone-sensitive lipase produces free fatty acids that are eventually converted to acetyl-coA by beta-oxidation. [citation needed]
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In addition to the liver, fructose is metabolized in the intestines, testis, kidney, skeletal muscle, fat tissue and brain, [5] [6] but it is not transported into cells via insulin-sensitive pathways (insulin regulated transporters GLUT1 and GLUT4). Instead, fructose is taken in by GLUT5. Fructose in muscles and adipose tissue is phosphorylated ...
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