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Ibuprofen was derived from propionic acid by the research arm of Boots Group during the 1960s. [81] The name is derived from the 3 functional groups: isobutyl (ibu) propionic acid (pro) phenyl (fen). [82] Its discovery was the result of research during the 1950s and 1960s to find a safer alternative to aspirin.
Ibuprofen, an analgesic and non-steroidal anti-inflammatory drug (NSAID), [1] is sold under many brand-names around the world. The most common are Brufen (its earliest registered trademark), Advil, Motrin, and Nurofen .
The brand first entered the American market in 1984 through Whitehall [3] (itself a division of Wyeth, which was purchased by Pfizer in 2009), [4] the same year ibuprofen gained Food and Drug Administration (FDA) approval for over-the-counter (OTC) sales in the United States (being available via prescription since 1974). [5]
The profens are a class of nonsteroidal anti-inflammatory drugs. [1] Profens are also known as 2-arylpropionic acids to reflect their chemical structure. [2] The most common example of a profen is ibuprofen, which has been sold under the brand name Profen among others.
[1] [2] It is updated at least once per year as required by the World Anti-Doping Code. [3] [4] The adoption of the first World Anti-Doping Code (the Code) occurred at the 2nd World Conference on Doping in Sport in March 2003 in Copenhagen, Denmark. It was there that WADA assumed the responsibility of maintaining, updating, and publishing the ...
Stewart Sanders Adams OBE (16 April 1923 – 30 January 2019) was an English pharmacist, and bioengineer who was part of a team from Boots which developed the painkiller ibuprofen in 1961. Ibuprofen is now on the World Health Organization's Model List of Essential Medicines and is one of the world's best-selling drugs. [1]
Nurofen is a brand of range of pain-relief medication containing ibuprofen made by the English-Dutch company Reckitt Benckiser. [1] Introduced in 1983, the Nurofen brand was acquired following Reckitt Benckiser's acquisition of Boots healthcare international in 2005 for £1.93 billion, which included Nurofen, Strepsils, and Clearasil. [2]
Fenbufen is a nonsteroidal anti-inflammatory drug used to treat pain. [1]Fenbufen is a member of the propionic acid derivatives class of drugs. [2]It was introduced by American Cyanamid under the trade name Lederfen in the 1980s.
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