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It has several functions, such as the relaying of sensory and motor signals to the cerebral cortex [1] [2] and the regulation of consciousness, sleep, and alertness. [3] [4] Anatomically, it is a paramedian symmetrical structure of two halves (left and right), within the vertebrate brain, situated between the cerebral cortex and the midbrain.
The pedunculopontine nucleus (PPN) or pedunculopontine tegmental nucleus (PPT or PPTg) is a collection of neurons located in the upper pons in the brainstem. [1] [2] It is involved in voluntary movements, [3] arousal, and provides sensory feedback to the cerebral cortex and one of the main components of the ascending reticular activating system.
Neuroanatomists usually divide the vertebrate brain into six main subregions: the telencephalon (the cerebral hemispheres), diencephalon (thalamus and hypothalamus), mesencephalon (midbrain), cerebellum, pons and medulla oblongata, with the midbrain, pons and medulla often collectively called the brainstem. Each of these areas has a complex ...
A 3D medical animation still shot showing different parts of the midbrain. The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. [1] In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. [1]
Information about the structure and function of the human brain comes from a variety of experimental methods, including animals and humans. Information about brain trauma and stroke has provided information about the function of parts of the brain and the effects of brain damage. Neuroimaging is used to visualise the brain and record brain ...
The thalamus supplies all parts of the neocortex with afferents. [3] The main thalamocortical fibers extend from different nuclei of the thalamus and project to the visual cortex, somatosensory (and associated sensori-motor) cortex, and the auditory cortex in the brain. Thalamocortical radiations also innervate gustatory and olfactory pathways ...
In the human brain, the central lateral nucleus is a part of the anterior intralaminar nucleus in the thalamus. [1]: 2 The intralaminar nuclei project to many different regions of the brain, [2] The thalamus acts generally as a relay point for the brain for other areas of the brain to link to. The central lateral nucleus acts in a vital role in ...
Additionally, the VPN—and particularly the ventral intermediate nucleus of the VPN—have been implicated in the pathophysiology and modulation of oscillatory tremors as found in Parkinson's disease and essential tremor; accordingly, it is a target of deep brain stimulation in the treatment of such pathologies. [4]