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The phrase entourage effect was introduced in 1999. [9] [10] While originally identified as a novel method of endocannabinoid regulation by which multiple endogenous chemical species display a cooperative effect in eliciting a cellular response, the term has evolved to describe the polypharmacy effects of combined cannabis phytochemicals or whole plant extracts. [11]
Stoners and scientists disagree on the answer. Some ask for a new system.
"Skunk" refers to several named strains of potent cannabis, grown through selective breeding and sometimes hydroponics. It is a cross-breed of Cannabis sativa and C. indica (although other strains of this mix exist in abundance). Skunk cannabis potency ranges usually from 6% to 15% and rarely as high as 20%.
Broad-leafed C. indica plants in the Indian Subcontinent are traditionally cultivated for the production of charas, a form of hashish. Pharmacologically, C. indica landraces tend to have higher THC content than C. sativa strains. [15] [16] Some users report more of a "stoned" feeling and less of a "high" from C. indica when compared to C. sativa.
Mapping the morphological concepts to scientific names in the Small 1976 framework, "Sativa" generally refers to C. sativa subsp. indica var. indica, "Indica" generally refers to C. sativa subsp. i. kafiristanica (also known as afghanica), and "Ruderalis", being lower in THC, is the one that can fall into C. sativa subsp. sativa.
Cannabis strains is a popular name to refer to plant varieties of the monospecific genus Cannabis sativa L..They are either pure or hybrid varieties of the plant, which encompasses various sub-species C. sativa, C. indica, and C. ruderalis.
The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Strains used in medicine are often bred for high CBD content, and strains used for recreational purposes are usually bred for high THC content or for a specific chemical balance. Quantitative analysis of a plant's cannabinoid profile is often determined by gas chromatography (GC), or more reliably by gas chromatography combined with mass ...