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Intraductal papillomas of the breast are benign lesions with an incidence of approximately 2-3% in humans. [1] They result from abnormal proliferation of the epithelial cells lining the breast ducts. [2] Two types of intraductal papillomas are generally distinguished. The central type develops near the nipple.
Inflammatory papillary hyperplasia (IPH) is a benign lesion of the oral mucosa which is characterized by the growth of one or more nodular lesions, measuring about 2mm or less. [ 4 ] [ 5 ] The lesion almost exclusively involves the hard palate, and in rare instances, it also has been seen on the mandible.
A papilloma (plural papillomas or papillomata) (papillo-+ -oma) is a benign epithelial tumor [1] growing exophytically (outwardly projecting) in nipple-like and often finger-like fronds. In this context, papilla refers to the projection created by the tumor, not a tumor on an already existing papilla (such as the nipple).
The microscopic appearance of a nipple adenoma can be mistaken for carcinoma. [1] Other conditions that have similar symptoms and signs as nipple adenoma include Paget's disease of the breast, other intraductal papillomas, ductal carcinoma in situ (DCIS), syringomatous adenoma of the nipple and subareolar sclerosing duct hyperplasia.
Papillomatosis is skin surface elevation caused by hyperplasia and enlargement of contiguous dermal papillae. [1] These papillary projections of the epidermis form an undulating surface under microscopic examination.
Florid cutaneous papillomatosis (FCP) is an obligate paraneoplastic syndrome. FCP begins as the sudden onset of numerous cutaneous papillomas that are clinically indistinguishable from viral warts. The papillomas range from 1 to 3 mm in diameter may spread to involve the entire body, including the face.
211.3 Colon. Familial adenomatous polyposis; 212 Benign neoplasm of respiratory and intrathoracic organs 212.0 Nasal cavities middle ear and accessory sinuses; 212.1 Larynx; 212.2 Trachea; 212.3 Bronchus and lung; 212.4 Pleura; 212.5 Mediastinum; 212.6 Thymus; 212.7 Heart. Myxoma; Rhabdomyoma; 213 Benign neoplasm of bone and articular cartilage
Intraductal papillomas are non-cancerous lesions and commonest in women age 30 to 50. Divided into central and peripheral papillomas, nipple discharge is more frequently observed when they are central. [10] Up to half of women with intraductal papillomas may present with bloody nipple discharge, but it can also be straw-coloured. [4]