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Although the exact mechanism explaining the clinical manifestations of autoimmune pancreatitis remain for an important part obscure, most professionals would agree that the development of IgG4 antibodies, recognizing an epitiope on the membrane of pancreatic ancinar cells is an important factor in the pathophysiology of the disease.
PANC-1 is a human pancreatic cancer cell line isolated from a pancreatic carcinoma of ductal cell origin. [1]PANC-1 was derived from the tissue of a 56-year-old male. The cells can metastasize but have poor differentiation abilities. [2]
Pancreatic cancer is the fifth most-common cause of cancer-related deaths in the United States, [8] and the seventh most-common in Europe. [9] In 2008, globally there were 280,000 new cases of pancreatic cancer reported and 265,000 deaths. [10] These cancers are classified as endocrine or nonendocrine tumors. The most common is ductal ...
The following is a list of cancer types. Cancer is a group of diseases that involve abnormal increases in the number of cells , with the potential to invade or spread to other parts of the body. [ 1 ]
The up regulation of matri-cellular proteins such as galectin-1, and tenascin-C is present in the stromal tissues of pancreatic cancer and chronic pancreatitis. [6] Matricellular proteins induce proliferation, migration and production of cytokines, ECM and angiogenic responses in PaSCs, which in turn induce cancer cell proliferation. [6]
Small intestinal bacterial overgrowth (SIBO), also termed bacterial overgrowth, or small bowel bacterial overgrowth syndrome (SBBOS), is a disorder of excessive bacterial growth in the small intestine. Unlike the colon (or large bowel), which is rich with bacteria, the small bowel usually has fewer than 100,000 organisms per millilitre. [1]
Pop star and actress Selena Gomez responded to body shamers on social media by revealing she has SIBO, a rare GI disorder with no cure. SIBO causes abdominal discomfort and symptoms like excess ...
Pancreatic acinar metaplasia (PAM) is a common incidental histopathologic finding present in approximately 20-25% of patients undergoing an esophagogastroduodenoscopy. [ 1 ] [ 2 ] Signs and symptoms