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Insulin lispro, sold under the brand name Humalog among others, is a modified type of medical insulin used to treat type 1 and type 2 diabetes. [5] It is delivered subcutaneously either by injection or from an insulin pump. [5] [6] Onset of effects typically occurs within 30 minutes and lasts about 5 hours. [5]
Basal insulin: the insulin that controls blood glucose levels between meals and overnight. It controls glucose in the fasting state. Boluses: the insulin that is released when food is eaten or to correct a high reading. Another device used in intensive insulinotherapy is the injection port. An injection port is a small disposable device ...
Insulin lispro (Humalog) Insulin aspart (Novolog) Insulin glulisine (Apidra) Examples of short-acting insulins (peak 2–4 hours) are: Regular insulin (Humulin R, Novolin R) Prompt insulin zinc (Semilente) Examples of intermediate-acting insulins (peak 4–10 hours) are: Isophane insulin, neutral protamine Hagedorn (NPH) (Humulin N, Novolin N)
Insulin Lispro Injection was also priced 50% lower than the list price of Humalog U-100. Lilly said that since then 10% of people using Humalog have transitioned to the cheaper injection.
A non-insulin medication approved by the U.S. Food and Drug Administration for treating type 1 diabetes is the amylin analog pramlintide, which replaces the beta-cell hormone amylin. Addition of pramlintide to mealtime insulin injections reduces the boost in blood sugar after a meal, improving blood sugar control. [57]
Eli Lilly said on Wednesday it will cut list prices by 70% for its most commonly prescribed insulin products, Humalog and Humulin, beginning from the fourth quarter of this year.
1996 Lilly Humalog "insulin lispro INN" approved by the U.S. Food and Drug Administration; 2003 Aventis Lantus "glargine" insulin analogue approved in USA [26]
Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922. [85] [86] This is a chronology of key milestones in the history of the medical use of insulin. For more details on the discovery, extraction, purification, clinical use, and synthesis of insulin, see Insulin