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This was from the notion that depression was primarily due to norepinephrine deficits, partly based on the fact that drugs that relieve depression increase brain norepinephrine levels. [28] To date, a great number of potent and selective and mixed norepinephrine reuptake inhibitors (NRIs) have been marketed as antidepressants. [ 11 ]
Sexual side effects. Some antidepressants, including commonly prescribed ones from the class known as SSRIs (selective serotonin reuptake inhibitors), can cause sexual side effects such as ...
What’s more, once a person has tried two different antidepressants, stayed with each one for long enough to feel the effects, and doesn’t get relief, their depression is considered treatment ...
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
The risk of liver damage appears to be only for patients already at risk, unlike the antidepressant nefazodone, which, though rare, can spontaneously cause liver failure in healthy patients. [13] Duloxetine is also approved for major depressive disorder (MDD), generalized anxiety disorder (GAD), diabetic neuropathy, chronic musculoskeletal pain ...
MAOIs such as moclobemide are reported to have a relatively fast onset of action compared to other antidepressant drug classes, [18] and have good long-term tolerability in terms of side effects. [19] Tolerance does not seem to occur; research has found that moclobemide retains its beneficial therapeutic properties in depression for at least a ...
Agomelatine, sold under the brand names Valdoxan and Thymanax, among others, is an atypical antidepressant most commonly used to treat major depressive disorder and generalized anxiety disorder. [8] One review found that it is as effective as other antidepressants with similar discontinuation rates overall but fewer discontinuations due to side ...
Adults taking antidepressants who want to come off their medication should not go cold turkey and should instead use a “staged” approach, experts have said. ... work and only when side-effects ...