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A much less common use of cholecalciferol therapy in rickets utilizes a single large dose and has been called stoss therapy. [28] [29] [30] Treatment is given either orally or by intramuscular injection of 300 000 IU (7500 μg) to 500 000 IU (12 500 μg = 12.5 mg), in a single dose, or sometimes in two to four divided doses. There are concerns ...
Daily dose regimens are preferred to admission of large doses at weekly or monthly schedules, and D 3 may be preferred over D 2, but there is a lack of consensus as to optimal type, dose, duration or what to measure to deem success. Daily regimens on the order of 4,000 IU/day (for other than infants) have a greater effect on 25(OH)D recovery ...
The upper limit per day for everyone over 9 years old is 4000 IUs, unless you’ve been screened by your doctor and have issues specific to you that they feel require a higher dose. Extremely high ...
Ish-Shalom et al. [69] performed a study in elderly women to compare the efficacy and safety of a daily dose of 1500 IU to a weekly dose of 10 500 IU and to a dose of 45 000 IU given every 28 days for two months. They concluded that supplementation with vitamin D can be equally achieved with daily, weekly, or monthly dosing frequencies.
Vitamin D3, aka cholecalciferol, is important for bone health and immune function. Experts discuss benefits, sources, risks and who needs a supplement. How to get the most out of vitamin D3
The recommended dietary allowance is 15 μg/d (600 IU per day; 800 IU for those over 70 years). Overdose has been observed at 1,925 μg/d (77,000 IU per day). [citation needed] Acute overdose requires between 15,000 μg/d (600,000 IU per day) and 42,000 μg/d (1,680,000 IU per day) over a period of several days to months.
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