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Fexofenadine, sold under the brand name Allegra among others, [10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria. [ 11 ] Therapeutically, fexofenadine is a selective peripheral H 1 blocker .
It contains fexofenadine, as the hydrochloride, an antihistamine; and pseudoephedrine, as the hydrochloride, a nasal decongestant. [ 2 ] In 2021, it was the 279th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.
The drug has been used in more ... tinnitus, blurred vision, ataxia, chest pain ... — contains 120 mg of pseudoephedrine hydrochloride (also 60 mg of fexofenadine).
Adverse drug reactions are most commonly associated with the first-generation H 1-antihistamines. This is due to their relative lack of selectivity for the H 1-receptor and their ability to cross the blood–brain barrier. The most common adverse effect is sedation; this "side-effect" is utilized in many OTC sleeping-aid preparations.
Naproxen/pseudoephedrine, sold under the brand name Aleve-D among others, is a fixed-dose combination medication used for the treatment of nasal congestion and other symptoms of the common cold. [1] It contains naproxen, as the sodium salt, a nonsteroidal anti-inflammatory drug (NSAID); and pseudoephedrine, as the hydrochloride, a nasal ...
In October 2020, the U.S. Food and Drug Administration (FDA) required the drug label to be updated for all nonsteroidal anti-inflammatory medications to describe the risk of kidney problems in unborn babies that result in low amniotic fluid. [3] [4] They recommend avoiding NSAIDs in pregnant women at 20 weeks or later in pregnancy. [3] [4]
The use of sedating drugs alongside hydroxyzine can cause oversedation and confusion if administered at high doses—any form of hydroxyzine treatment alongside sedatives should be done under the supervision of a doctor. [28] [25] Because of the potential for more severe side effects, this drug is on the list to avoid in the elderly. [29]
Diphenhydramine, available in various salt forms, [74] such as citrate, [75] [76] hydrochloride, [77] and salicylate, [78] exhibits distinct molecular weights and pharmacokinetic properties. Specifically, diphenhydramine hydrochloride and diphenhydramine citrate possess molecular weights of 291.8 g/mol [79] and 447.5 g/mol, [80] respectively ...