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Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [ 8 ] [ 9 ] [ 10 ] For acne, it is applied to the skin as a cream, gel or ointment. [ 10 ]
By October 2015, a "bottle of 30 of Solodyn tablets can cost up to $1,040.41" and an "8-milliliter bottle of Jublia costs $1,075.72" according to "Truven Health Analytics, which publishes average wholesale prices."
By 2012 the price of a vial of Acthar was $28,400. [90] and was considered to be one of the world's most expensive drugs in 2013. By 2014 the price of Gilead's specialty drug for hepatitis C, Sovaldi or sofosbuvir, was $84,000 to $168,000 for a course of treatment in the U.S., £35,000 in the UK for 12 weeks. [92]
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Hydroquinone is a commonly used agent in skin whiteners. The European Union banned it from cosmetics in 2000. [9] It works by decreasing melanin production. [9]Tretinoin, also known as all-trans retinoic acid, may be used to whiten specific areas. [6]
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Fluocinolone acetonide (0.01%)/Hydroquinone (4%)/ Tretinoin (0.05%) Cream is indicated for the short-term (up to 8 weeks) treatment of moderate to severe melasma of the face in the presence of measures for sun avoidance, including the use of sunscreens.
Tretinoin/benzoyl peroxide, sold under the brand name Twyneo, is a fixed-dose combination medication used for the treatment of acne. [1] [2] It contains tretinoin, a vitamin A derivative, and benzoyl peroxide, an oxidizing agent. [3] The combination was approved for medical use in the United States in July 2021. [2] [4] [5]