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  2. Atipamezole - Wikipedia

    en.wikipedia.org/wiki/Atipamezole

    Atipamezole has also been used as an antidote for various toxicities in dogs. For example, the anti-tick medication amitraz is commonly ingested by dogs who eat their anti-tick collars. [19] Amitraz works by the same mechanism as dexmedetomidine and is thus easily reversed by atipamezole.

  3. Maropitant - Wikipedia

    en.wikipedia.org/wiki/Maropitant

    Side effects in dogs and cats include hypersalivation, diarrhea, loss of appetite, and vomiting. [12] [16] Eight percent of dogs taking maropitant at doses meant to prevent motion sickness vomited right after, likely due to the local effects maropitant had on the gastrointestinal tract. Small amounts of food beforehand can prevent such post ...

  4. Grapiprant - Wikipedia

    en.wikipedia.org/wiki/Grapiprant

    The approximate calculation for canine efficacy dose is between the range of 1.3 and 1.7 mg/kg, in conjunction with a methylcellulose suspending agent. Based on the calculations from the comparisons of binding affinity of grapiprant to the EP4 receptors of dogs, rats, and humans, the study of plasma and serum protein binding determinations, the ...

  5. Bedinvetmab - Wikipedia

    en.wikipedia.org/wiki/Bedinvetmab

    Half the dogs received bedinvetmab and half the dogs received a sterile saline injection every 28 days for a total of three doses. [5] Before treatment and on various days throughout the study, owners used the Canine Brief Pain Inventory (CBPI) assessment tool to measure the severity of the dog's pain and the degree to which the pain interfered ...

  6. Apamin - Wikipedia

    en.wikipedia.org/wiki/Apamin

    In mice, the injection of apamin produces convulsions and long-lasting spinal spasticity. Also, it is known that the polysynaptic spinal reflexes are disinhibited in cats. [ 12 ] Polysynaptic reflex is a reflex action that transfers an impulse from a sensory neuron to a motor neuron via an interneuron in the spinal cord. [ 13 ]

  7. Pimobendan - Wikipedia

    en.wikipedia.org/wiki/Pimobendan

    Pimobendan is indicated for the management of the signs of mild, moderate, or severe congestive heart failure in dogs due to clinical myxomatous mitral valve disease (MMVD) or dilated cardiomyopathy (DCM); [1] [7] and for use with concurrent therapy for congestive heart failure (e.g.,furosemide, etc.) as appropriate on a case-by-case basis. [1]

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