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Checkpoint inhibitor therapy is a form of cancer immunotherapy. The therapy targets immune checkpoints, key regulators of the immune system that when stimulated can dampen the immune response to an immunologic stimulus. Some cancers can protect themselves from attack by stimulating immune checkpoint targets.
Cancer Therapy by Inhibition of Negative Immune Regulation (CTLA4, PD1) A2AR & A2BR: The Adenosine A2A receptor is regarded as an important checkpoint in cancer therapy because adenosine in the immune microenvironment, leading to the activation of the A2a receptor, is negative immune feedback loop and the tumor microenvironment has relatively high concentrations of adenosine. [27]
One way to potentially improve vaccine therapy is by combining the vaccine with other types of immunotherapy aimed at stimulating the immune system. Since tumors often evolve mechanisms to suppress the immune system, immune checkpoint blockade has recently received a lot of attention as a potential treatment to be combined with vaccines. For ...
This is a list of types of medical therapy, including forms of traditional medicine and alternative medicine. For psychotherapies and other behavioral and psychological intervention methods, see list of psychotherapies .
DNA damage checkpoint is a signal transduction pathway that blocks cell cycle progression in G1, G2 and metaphase and slows down the rate of S phase progression when DNA is damaged. It leads to a pause in cell cycle allowing the cell time to repair the damage before continuing to divide.
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Harlene Anderson (born 1942) is an American psychologist and a cofounder of the Postmodern Collaborative Approach to therapy. In the 1980s, Anderson and her colleague Harold A. Goolishian pioneered a new technique that is used to relate to patients within therapy through language and collaboration, and without the use of diagnostic labels.
Positive psychotherapy (PPT) is a therapeutic approach developed by Nossrat Peseschkian during the 1970s and 1980s. [2] [3] [4] Initially known as "differentiational analysis", it was later renamed as positive psychotherapy when Peseschkian published his work in 1977, which was subsequently translated into English in 1987.
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