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8851 12569 Ensembl ENSG00000176749 ENSMUSG00000048895 UniProt Q15078 P61809 RefSeq (mRNA) NM_003885 NM_009871 RefSeq (protein) NP_003876 NP_034001 Location (UCSC) Chr 17: 32.49 – 32.49 Mb Chr 11: 80.37 – 80.37 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cyclin-dependent kinase 5 activator 1 is an enzyme that in humans is encoded by the CDK5R1 gene. Function The protein ...
Cholinesterase reactivators are drugs that reverse the inhibition of cholinesterase by organophosphates or sulfonates. [1] They are used as antidote for treating organophosphate insecticide and nerve agent poisoning. [ 2 ]
A transcriptional activator is a protein (transcription factor) that increases transcription of a gene or set of genes. [1] Activators are considered to have positive control over gene expression, as they function to promote gene transcription and, in some cases, are required for the transcription of genes to occur.
12568 Ensembl ENSG00000164885 ENSMUSG00000028969 UniProt Q00535 P49615 RefSeq (mRNA) NM_001164410 NM_004935 NM_007668 RefSeq (protein) NP_001157882 NP_004926 NP_031694 Location (UCSC) Chr 7: 151.05 – 151.06 Mb Chr 5: 24.62 – 24.63 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cyclin-dependent kinase 5 is a protein, and more specifically an enzyme, that is encoded by the Cdk5 ...
In the human genome, STAT6 protein is encoded by the STAT6 gene, located on the chromosome 12q13.3-q14.1. [6] The gene encompasses over 19 kb and consists of 23 exons . [ 7 ] STAT6 shares structural similarity with the other STAT proteins and is composed of the N-terminal domain , DNA binding domain , SH3- like domain, SH2 domain and ...
Signal transducer and activator of transcription 5 (STAT5) refers to two highly related proteins, STAT5A and STAT5B, which are part of the seven-membered STAT family of proteins. Though STAT5A and STAT5B are encoded by separate genes , the proteins are 90% identical at the amino acid level. [ 1 ]
[2] [3] Binding of the activator-coactivator complex increases the speed of transcription by recruiting general transcription machinery to the promoter, therefore increasing gene expression. [3] [4] [5] The use of activators and coactivators allows for highly specific expression of certain genes depending on cell type and developmental stage. [2]
Activator may refer to: Activator (genetics) , a DNA-binding protein that regulates one or more genes by increasing the rate of transcription Activator (phosphor) , a type of dopant used in phosphors and scintillators