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Calcitonin. Calcitonin is a 32 amino acid peptide hormone secreted by parafollicular cells (also known as C cells) of the thyroid (or endostyle) in humans and other chordates [5] in the ultimopharyngeal body. [6] It acts to reduce blood calcium (Ca 2+), opposing the effects of parathyroid hormone (PTH). [7]
Calcitonin receptor. The calcitonin receptor (CT) is a G protein-coupled receptor that binds the peptide hormone calcitonin and is involved in maintenance of calcium homeostasis, [5] particularly with respect to bone formation and metabolism. [6][7][8]
Calcium metabolism is the movement and regulation of calcium ions (Ca 2+) in (via the gut) and out (via the gut and kidneys) of the body, and between body compartments: the blood plasma, the extracellular and intracellular fluids, and bone. Bone acts as a calcium storage center for deposits and withdrawals as needed by the blood via continual ...
Vitamin D 5. sitocalciferol. (made from 7-dehydrositosterol) Several forms (vitamers) of vitamin D exist, with the two major forms being vitamin D 2 or ergocalciferol, and vitamin D 3 or cholecalciferol. [ 1 ] The term 'vitamin D' refers to either D 2 or D 3, or both, and is known collectively as calciferol.
InterPro. Calcitonin gene-related peptide (CGRP) is a member of the calcitonin family of peptides consisting of calcitonin, amylin, adrenomedullin, adrenomedullin 2 (intermedin) and calcitonin‑receptor‑stimulating peptide. Calcitonin is mainly produced by thyroid C cells whilst CGRP is secreted and stored in the nervous system. [1]
Calcium signaling. Shows Ca 2+ release from the endoplasmic reticulum through phospholipase C (PLC) pathway. Calcium signaling is the use of calcium ions (Ca 2+) to communicate and drive intracellular processes often as a step in signal transduction. Ca 2+ is important for cellular signalling, for once it enters the cytosol of the cytoplasm it ...
The U.S. Institute of Medicine (IOM) established Recommended Dietary Allowances (RDAs) for calcium in 1997 and updated those values in 2011. [6] See table. The European Food Safety Authority (EFSA) uses the term Population Reference Intake (PRIs) instead of RDAs and sets slightly different numbers: ages 4–10 800 mg, ages 11–17 1150 mg, ages 18–24 1000 mg, and >25 years 950 mg. [10]
PubMed search. [3] [4] Wikidata. View/Edit Human. View/Edit Mouse. Parathyroid hormone (PTH), also called parathormone or parathyrin, is a peptide hormone secreted by the parathyroid glands that regulates the serum calcium concentration through its effects on bone, kidney, and intestine. [5] PTH influences bone remodeling, which is an ongoing ...