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Vasculitis [3] Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [4] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [3][5] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [2]
The following is a list of psychedelic drugs of various chemical classes, including both naturally occurring and synthetic compounds. Serotonergic psychedelics are usually considered the "classical" psychedelics [dubious – discuss], whereas the other classes are often seen as having only secondary psychedelic properties; nonetheless all of the compounds listed here are considered ...
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". [ 2 ][ 3 ] Also referred to as classic hallucinogens or serotonergic hallucinogens, the term psychedelic is sometimes used more broadly to ...
Drug overdose and intoxication are significant causes of accidental death and can also be used as a form of suicide. Death can occur from overdosing on a single or multiple drugs, or from combined drug intoxication (CDI) due to poly drug use. Poly drug use often carries more risk than use of a single drug, due to an increase in side effects ...
Overall, it is estimated that 5.66 million adults in the US population reported current vaping 2.3%. From those users in the population, more than 2.21 million were current cigarette smokers (39.1%), more than 2.14 million were former smokers (37.9%), and more than 1.30 million were never smokers (23.1%).
Methamphetamine (METH) is a potent amphetamine-type stimulant that has high abuse potential and can be smoked, snorted, injected, or taken orally. The drug is high in lipid solubility and can cross the blood-brain barrier more readily than amphetamine due to the addition of an extra methyl group.
Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for chronic pain and also for opioid use disorder. [7] It is used to treat chronic pain, and it is also used to treat addiction to heroin or other opioids. [10][11] Prescribed for daily use, the medicine relieves cravings and removes ...
Amphetamine is a weak base with a pK a of 9.9; [3] consequently, when the pH is basic, more of the drug is in its lipid soluble free base form, and more is absorbed through the lipid-rich cell membranes of the gut epithelium. [3] [29] Conversely, an acidic pH means the drug is predominantly in a water-soluble cationic (salt) form, and less is ...
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