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Zavegepant is a calcitonin gene-related peptide receptor antagonist. [1] It is sprayed into the nose. [1] It is sold by Pfizer. [1] The most common adverse reactions include taste disorders, nausea, nasal discomfort, and vomiting. [1] Zavegepant was approved for medical use in the United States in March 2023. [1] [2] [3] [4]
Calcitonin is a 32 amino acid peptide hormone secreted by parafollicular cells ... In addition to the injectable and nasal spray dosage forms of the salmon calcitonin ...
Calcitonin, as salmon calcitonin (sCT), is available in the pharmaceutical market as an injectable preparation for intravenous, intramuscular or subcutaneous application. Noninvasive sCT preparation as a nasal spray is commercially produced and received US FDA approval under the proprietary name Miacalcin® in 1975 for the treatment of ...
If a patient attempts to use a nasal spray treatment while they have allergic rhinitis (i.e., a runny nose), that thick mucus can make it difficult for the medication in a nasal spray to penetrate ...
Intranasal calcitonin, calcitonin-salmon, is used to treat hypercalcaemia arising out of malignancy, Paget's disease of bone, post menopausal and steroid induced osteoporosis, phantom limb pain and other metabolic bone abnormalities, available as Rockbone, Fortical and Miacalcin Nasal Spray.
Calcitonin gene-related ... Drugs of this class have also been investigated for use in osteoarthritis. [6 ... is a nasal spray approved for acute treatment of ...
The U.S. Food and Drug Administration expanded approval for Johnson & Johnson’s nasal spray, Spravato, to allow it to be used as a standalone treatment for patients with severe depression, the ...
Additionally, there is question of the overall efficacy of calcitonin-containing nasal sprays. A phase III trial found no difference between placebo and nasal calcitonin sprays on lumbar bone mineral density in osteoporosis. [34] It did find a significant increase in bone mineral density with oral calcitonin.
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