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  2. Chromosomal inversion - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_inversion

    An inversion is a chromosome rearrangement in which a segment of a chromosome becomes inverted within its original position. An inversion occurs when a chromosome undergoes a two breaks within the chromosomal arm, and the segment between the two breaks inserts itself in the opposite direction in the same chromosome arm.

  3. Biological applications of bifurcation theory - Wikipedia

    en.wikipedia.org/wiki/Biological_applications_of...

    Example of a biological network between genes and proteins that controls entry into S phase. However, with knowledge of network interactions and a set of parameters for the proteins and protein interactions (usually obtained through empirical research), it is often possible to construct a model of the network as a dynamical system .

  4. Reverse genetics - Wikipedia

    en.wikipedia.org/wiki/Reverse_genetics

    Reverse genetics is a method in molecular genetics that is used to help understand the function(s) of a gene by analysing the phenotypic effects caused by genetically engineering specific nucleic acid sequences within the gene.

  5. Transposable element - Wikipedia

    en.wikipedia.org/wiki/Transposable_element

    A bacterial DNA transposon. A transposable element (TE), also transposon, or jumping gene, is a type of mobile genetic element, a nucleic acid sequence in DNA that can change its position within a genome, sometimes creating or reversing mutations and altering the cell's genetic identity and genome size.

  6. Retrotransposon - Wikipedia

    en.wikipedia.org/wiki/Retrotransposon

    Through reverse transcription, retrotransposons amplify themselves quickly to become abundant in eukaryotic genomes such as maize (49–78%) [3] and humans (42%). [4] They are only present in eukaryotes but share features with retroviruses such as HIV, for example, discontinuous reverse transcriptase-mediated extrachromosomal recombination. [5] [6]

  7. Umpolung - Wikipedia

    en.wikipedia.org/wiki/Umpolung

    In this example, the β-carbon of the α,β-unsaturated ester 1 formally acts as a nucleophile, [4] whereas normally it would be expected to be a Michael acceptor. Scheme 3. Umpolung of Michael Acceptors. This carbene reacts with the α,β-unsaturated ester 1 at the β-position forming the intermediate enolate 2.

  8. Complementarity (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Complementarity_(molecular...

    In nature complementarity is the base principle of DNA replication and transcription as it is a property shared between two DNA or RNA sequences, such that when they are aligned antiparallel to each other, the nucleotide bases at each position in the sequences will be complementary, much like looking in the mirror and seeing the reverse of things.

  9. Position effect - Wikipedia

    en.wikipedia.org/wiki/Position_effect

    Position effect is the effect on the expression of a gene when its location in a chromosome is changed, often by translocation. This has been well described in Drosophila with respect to eye color and is known as position effect variegation (PEV). [1] The phenotype is well characterised by unstable expression of a gene that results in the red ...