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Multiregional evolution holds that the human species first arose around two million years ago and subsequent human evolution has been within a single, continuous human species. This species encompasses all archaic human forms such as Homo erectus , Denisovans , and Neanderthals as well as modern forms, and evolved worldwide to the diverse ...
Modern scientific views find little merit in any polygenic model due to an increased understanding of speciation in a human context, with the monogenic "Out of Africa" hypothesis and its variants being the most widely accepted models for human origins. [1]
At present the best-understood examples of polygenic adaptation are in humans, and particularly for height, a trait that can be interpreted using data from genome-wide association studies. In a 2012 paper, Joel Hirschhorn and colleagues showed that there was a consistent tendency for the "tall" alleles at genome-wide significant loci to be at ...
The infinitesimal model, also known as the polygenic model, is a widely used statistical model in quantitative genetics and in genome-wide association studies.Originally developed in 1918 by Ronald Fisher, it is based on the idea that variation in a quantitative trait is influenced by an infinitely large number of genes, each of which makes an infinitely small (infinitesimal) contribution to ...
Recent human evolution refers to evolutionary adaptation, sexual and natural selection, and genetic drift within Homo sapiens populations, since their separation and dispersal in the Middle Paleolithic about 50,000 years ago. Contrary to popular belief, not only are humans still evolving, their evolution since the dawn of agriculture is faster ...
Molecular anthropology, also known as genetic anthropology, is the study of how molecular biology has contributed to the understanding of human evolution. [1] This field of anthropology examines evolutionary links between ancient and modern human populations, as well as between contemporary species.
A language model AI created proteins as good as ones honed over a million years of evolution. The implications are staggering. AI Has Successfully Imitated Human Evolution—and Might Do It Even ...
Population genetics must either model this complexity in detail, or capture it by some simpler average rule. Empirically, beneficial mutations tend to have a smaller fitness benefit when added to a genetic background that already has high fitness: this is known as diminishing returns epistasis. [ 21 ]