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The anticonvulsant drug, lamotrigine, has been associated with a decrease in white blood cell count. [ 2 ] The FDA monograph for metronidazole states that this medication can also cause leukopenia, and the prescriber information suggests a complete blood count, including differential cell count, before and after, in particular, high-dose therapy.
Adults need about 2.4 micrograms of B12 a day (that much can be found in one portion of salmon, canned tuna or ground beef), with pregnant and nursing women needing slightly more (2.6 and 2.8 mcg ...
Medications: long-term use of certain medications can result in poor absorption of dietary vitamin B 12. [1] These include medications to treat heartburn, and metformin to treat diabetes. [131] [132] A genetic disorder, transcobalamin II deficiency, or Imerslund–Gräsbeck syndrome can be a cause. Nitrous oxide exposure, and recreational use ...
Neuropsychiatric symptoms can precede hematological signs and are often the presenting manifestation of the disease. [55] Vitamin B 12 serum levels are used to detect its deficiency, but do not distinguish its causes. Vitamin B 12 levels can be falsely high or low and data for sensitivity and specificity vary widely.
ICD-10 coding number Diseases Database coding number Medical Subject Headings plasma cell leukemia: C90.1: D007952 Plasma cell leukemia (PCL), a lymphoproliferative disorder, [79] is a rare cancer involving a subtype of white blood cells called plasma cells. [80] Acute erythraemia and erythroleukaemia: Acute erythremic myelosis: Acute erythroid ...
Urine culture is quantitative and very reliable, but can take at least one day to obtain a result and it is expensive. [ 8 ] [ 14 ] Miniaturization of bacterial culture within dipstick format, Digital Dipstick, [ 15 ] allows bacterial detection, identification and quantification for bacteriuria within 10–12 hours at the point-of-care .
Pyuria is the condition of urine containing white blood cells or pus. Defined as the presence of 6-10 or more neutrophils per high power field of unspun, voided mid-stream urine, it can be a sign of a bacterial urinary tract infection. Pyuria may be present in people with sepsis, or in older people with pneumonia.
Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says.