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Intellia Therapeutics, Inc. is an American clinical-stage biotechnology company focused on developing novel, potentially curative therapeutics leveraging CRISPR-based technologies. The company's in vivo programs use intravenously administered CRISPR as the therapy, in which the company's proprietary delivery technology enables highly precise ...
In 2023, the company announced that it will focus on developing CRISPR-based therapies. [8] The company's platform uses "ultra-small" Cas enzymes, such as CasΦ and Cas14, which measure down to a third or less the size of Cas9, and which could allow for easier delivery in vivo through commonly used non-viral and viral delivery mechanisms ...
The company is headquartered in Cambridge, Massachusetts. In the development of therapies, the company relies on CRISPR and prime editing , whereby single nucleotides in a DNA sequence can be modified without cutting the DNA, theoretically reducing the likelihood of off-target effects compared to previous CRISPR-based methods [ vague ] .
Sherlock Biosciences is a biotechnology company based in Cambridge, Massachusetts developing diagnostic tests using CRISPR-Cas13.The company was founded in 2019 [1] by Feng Zhang, Jim Collins, Omar Abudayyeh, and Jonathan Gootenberg of the Broad Institute.
CRISPR Therapeutics is applying this technology platform to research, develop and commercialize medicines for various diseases including sickle cell disease, beta thalassemia, various cancers, type 1 diabetes, and cardiovascular diseases. [7] The CEO is Samarth Kulkarni, PhD, who joined the company in 2015 as chief business officer.
LNP technology is crucial to Moderna's vaccine development efforts, and the patent ruling could increase pressure on the Cambridge, Massachusetts-based firm to pay for a license to Arbutus' patent ...
LONDON (Reuters) -The Bill & Melinda Gates Foundation has given $23.6 million to U.S.-based life science company Micron Biomedical to fund the first ever mass production of needle-free vaccine ...
[16] [17] TALEN and CRISPR are the two most commonly used and each has its own advantages. [18] TALENs have greater target specificity, while CRISPR is easier to design and more efficient. [18] The development of the CRISPR-Cas9 gene editing system has effectively halved the amount of time needed to develop genetically modified animals. [19