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Alternative online IC50 calculator (www.ic50.org) based on Python, NumPy, SciPy and Matplotlib; ELISA IC50/EC50 Online Tool (link seems broken) IC50 to pIC50 calculator; Online tool for analysis of in vitro resistance to antimalarial drugs; IC50-to-Ki converter of an inhibitor and enzyme that obey classic Michaelis-Menten kinetics
Lipophilic efficiency [1] (LiPE), sometimes referred to as ligand-lipophilicity efficiency (LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research compounds, linking potency and lipophilicity in an attempt to estimate druglikeness.
The single-ended primary-inductor converter (SEPIC) is a type of DC/DC converter that allows the electrical potential at its output to be greater than, less than, or equal to that at its input. The output of the SEPIC is controlled by the duty cycle of the electronic switch (S1).
Inhibitors have IC50 values so I tried to reintegrate it with information already present in the article. I think that including it in the lead paragraph would mislead people into thinking it was a discussion about inhibitors not The IC50 concept Lilypink 19:04, 5 November 2007 (UTC) IC50 is not a pharmacological constant! pA2 is a constant.
For competition binding assays and functional antagonist assays IC 50 is the most common summary measure of the dose-response curve. For agonist/stimulator assays the most common summary measure is the EC 50. [6] The EC 50 is also related to IC 50 which is a measure of a compound's inhibition (50% inhibition).
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IC should not be confused with the similar photoelectric effect. When a gamma ray emitted by the nucleus of an atom hits another atom, it may be absorbed producing a photoelectron of well-defined energy (this used to be called "external conversion"). In IC, however, the process happens within one atom, and without a real intermediate gamma ray.
In electronics, a transimpedance amplifier (TIA) is a current to voltage converter, almost exclusively implemented with one or more operational amplifiers. The TIA can be used to amplify [ 1 ] the current output of Geiger–Müller tubes , photo multiplier tubes, accelerometers , photo detectors and other types of sensors to a usable voltage.