Search results
Results from the WOW.Com Content Network
Below are several examples of differing types of local blood flow regulation by specific organ type or organ system. In each case, there is a specific type of intrinsic regulation occurring in order to maintain or alter blood flow to that given organ alone, instead of creating a systemic change that would affect the entire body.
Bayliss effect or Bayliss myogenic response is a special manifestation of the myogenic tone in the vasculature. [3] [4] The Bayliss effect in vascular smooth muscles cells is a response to stretch. This is especially relevant in arterioles of the body. When blood pressure is increased in the blood vessels and the blood vessels distend, they ...
Ambient temperature is an example of exogenous vasoconstriction. Cutaneous vasoconstriction will occur because of the body's exposure to the severe cold. Examples of endogenous factors include the autonomic nervous system, circulating hormones, and intrinsic mechanisms inherent to the vasculature itself (also referred to as the myogenic response).
Myogenic tone is a state of muscle tone in living creatures that originates from the muscle itself rather than from the autonomic nervous system or from hormone processes. It may be contrasted with neurogenic tone , which is created by actions of the autonomic nervous system.
Vascular resistance is the amount of force circulating blood must overcome in order to allow perfusion of body tissues. Narrow vessels create more vascular resistance, while dilated vessels decrease vascular resistance. Vasodilation acts to increase cardiac output by decreasing afterload, −one of the four determinants of cardiac output. [4]
This decrease in blood flow in the cerebral vascular system can result in a buildup of metabolic wastes generated by neurons and glial cells and a decrease in oxygen and glucose delivery to them. As a result, cellular energy failure, depolarization of neuronal and glial membranes, edema , and excess neurotransmitter and calcium ion release can ...
The cells of the neurovascular unit also make up the blood–brain barrier (BBB), which plays an important role in maintaining the microenvironment of the brain. [11] In addition to regulating the exit and entrance of blood, the blood–brain barrier also filters toxins that may cause inflammation, injury, and disease. [12]
A basal cell is a general cell type that is present in many forms of epithelial tissue throughout the body. Basal cells are located between the basement membrane and the remainder of the epithelium, effectively functioning as an anchor for the epithelial layer and an important mechanism in the maintenance of intraorgan homeostasis.