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Ménière's disease (MD) is a disease of the inner ear that is characterized by potentially severe and incapacitating episodes of vertigo, tinnitus, hearing loss, and a feeling of fullness in the ear. [3] [4] Typically, only one ear is affected initially, but over time, both ears may become involved. [3]
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
Ménétrier disease; Other names: Hypoproteinemic hypertrophic gastropathy: Biopsy of the stomach in Ménétrier disease; the substantial pit hyperplasia makes the large rugal folds appear to be covered by myriad polyps resembling hyperplastic polyps. The muscularis propria is the folded structure at the bottom center. Specialty: Gastroenterology
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Ménière's disease frequently presents with recurrent, spontaneous attacks of severe vertigo in combination with ringing in the ears , a feeling of pressure or fullness in the ear (aural fullness), severe nausea or vomiting, imbalance, and hearing loss. [9] [25] [38] As the disease worsens, hearing loss will progress.
Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which stops the vertigo attacks but causes permanent deafness. [19] Due to the effects on mitochondria, certain inherited mitochondrial disorders result in increased sensitivity to the toxic effects of aminoglycosides.
The disease, which is usually fatal for cattle, infects the central nervous system and leaves the animals with aggressive symptoms and a lack of coordination. Since 1995, 178 human deaths have ...
The threat of so-called “mad cow disease” has all but faded from the collective memory, after its appearance in U.K. cattle in 1986. Human deaths from the scourge, caused by eating ...
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