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Lipomas are rarely life-threatening, and the common subcutaneous lipomas are not a serious condition. Lipomas growing in internal organs can be more dangerous; for example, lipomas in the gastrointestinal tract can cause bleeding, ulceration, and painful obstructions (so-called "malignant by location", despite being a benign growth histologically).
The lipomas are well-encapsulated, slow-growing, benign fatty tumors. The distribution is defined as being focused in the trunk of the body and extremities. [2] Familial Multiple Lipomatosis can be identified when multiple lipomas occur in multiple family members that span different generations. [2] Some people may have hundreds of lipomas ...
Other entities which are accompanied by multiple lipomas include Proteus syndrome, Cowden syndrome and related disorders due to PTEN gene mutations, benign symmetric lipomatosis (Madelung disease), Dercum's Disease, familial lipodystrophy, hibernomas, epidural steroid injections with epidural lipomatosis, [6] and familial angiolipomatosis.
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[25] Although lipomas can develop at any age, they more commonly appear between the ages of 40 and 60. [24] Lipomas affect about 1% of the population, with no documented sex bias, and about 1 in every 1000 people will have a lipoma within their lifetime. [25] [26] The cause of lipomas is not well defined.
Dercum's disease is a rare condition characterized by multiple painful fatty tumors, called lipomas, that can grow anywhere in subcutaneous fat across the body. [1] Sometimes referred as adiposis dolorosa in medical literature, Dercum’s disease is more of a syndrome than a disease (because it has several clinically recognizable features, signs, and symptoms that are characteristic of it and ...
Chondroid lipoma is an uncommon soft tissue fatty tumor that can develop in deeper or superficial tissues. It often manifests as a painless mass. [3] The subcutis, superficial muscular fascia, or skeletal muscles of the limbs and limb girdles, trunk, head, and neck are where the majority of lesions are located. [4]
Gardner syndrome consists of adenomatous polyps of the gastrointestinal tract, Gardner fibromas, desmoid tumors, osteomas, epidermoid cysts, lipomas, dental abnormalities, and periampullary carcinomas. The incidence of the syndrome is 1:14,025 with an equal sex distribution.