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  2. Assessment of kidney function - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_kidney_function

    This filtrate then flows along the length of the nephron, which is a tubular structure lined by a single layer of specialized cells and surrounded by capillaries. The major functions of these lining cells are the reabsorption of water and small molecules from the filtrate into the blood, and the secretion of wastes from the blood into the urine.

  3. Proximal tubule - Wikipedia

    en.wikipedia.org/wiki/Proximal_tubule

    The proximal tubule is the segment of the nephron in kidneys which begins from the renal pole of the Bowman's capsule to the beginning of loop of Henle.At this location, the glomerular parietal epithelial cells (PECs) lining bowman’s capsule abruptly transition to proximal tubule epithelial cells (PTECs).

  4. Brush border - Wikipedia

    en.wikipedia.org/wiki/Brush_border

    Brush border cells are found mainly in the following organs: The small intestine tract: This is where absorption takes place. [2] [3] [4] The brush borders of the intestinal lining are the site of terminal carbohydrate digestions. The microvilli that constitute the brush border have enzymes for this final part of digestion anchored into their ...

  5. Distal convoluted tubule - Wikipedia

    en.wikipedia.org/wiki/Distal_convoluted_tubule

    The DCT is lined with simple cuboidal cells, the distal convoluted tubule cells, that are shorter than those of the proximal convoluted tubule (PCT). The lumen appears larger in the PCT than the DCT lumen because the PCT has a brush border (microvilli).

  6. Glomerular filtration rate - Wikipedia

    en.wikipedia.org/wiki/Glomerular_filtration_rate

    To allow comparison of results between people of different sizes, the C Cr is often corrected for the body surface area (BSA) and expressed compared to the average sized man as mL/min/1.73 m 2. While most adults have a BSA that approaches 1.7 m 2 (1.6 m 2 to 1.9 m 2 ), extremely obese or slim patients should have their C Cr corrected for their ...

  7. Kidney - Wikipedia

    en.wikipedia.org/wiki/Kidney

    Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and functional unit of the kidney. Each adult human kidney contains around 1 million nephrons, while a mouse kidney contains only ...

  8. Renal physiology - Wikipedia

    en.wikipedia.org/wiki/Renal_physiology

    This filtrate then flows along the length of the nephron, which is a tubular structure lined by a single layer of specialized cells and surrounded by capillaries. The major functions of these lining cells are the reabsorption of water and small molecules from the filtrate into the blood, and the secretion of wastes from the blood into the urine.

  9. Fanconi syndrome - Wikipedia

    en.wikipedia.org/wiki/Fanconi_syndrome

    Fanconi syndrome or Fanconi's syndrome (English: / f ɑː n ˈ k oʊ n i /, / f æ n-/) is a syndrome of inadequate reabsorption in the proximal renal tubules [1] of the kidney.The syndrome can be caused by various underlying congenital or acquired diseases, by toxicity (for example, from toxic heavy metals), or by adverse drug reactions. [2]