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Fesoterodine (INN, used as the fumarate under the brand name Toviaz) is an antimuscarinic drug developed by Schwarz Pharma AG to treat overactive bladder syndrome (OAB). [2] It was approved by the European Medicines Agency in April 2007, [3] the US Food and Drug Administration on October 31, 2008 [4] and Health Canada on February 9, 2012.
The most common symptoms of IC/BPS are suprapubic pain, [10] urinary frequency, painful sexual intercourse, [11] and waking up from sleep to urinate. [12]In general, symptoms may include painful urination described as a burning sensation in the urethra during urination, pelvic pain that is worsened with the consumption of certain foods or drinks, urinary urgency, and pressure in the bladder or ...
Pain while urinating suggests that there is a problem other than overactive bladder. [1] Specific treatment is not always required. [1] If treatment is desired pelvic floor exercises, bladder training, and other behavioral methods are initially recommended. [3]
Some drugs need to be used with caution in patients with renal dysfunction. The use of nitrofurantoin is contraindicated in patients with an estimated GFR of less than 30 mL/min/1.73m 2 as drug accumulation can lead to increased side effects and impaired recovery of the urinary tract, increasing the risk of treatment failure. [29]
The principal diagnostic tool for nocturia is the voiding bladder diary. Based on information recorded in the diary, a physician can classify the patient as having global polyuria, nocturnal polyuria, or bladder storage problems. A voiding bladder diary should record: [citation needed] number of voids; timing of voids; volume voided
The bladder is an organ that stores urine until it is released from the body. Several conditions can affect the bladder including urinary tract infections, bladder stones, bladder cancer, overactive bladder, cystitis, interstitial cystitis, abscess, fistula, and urinary incontinence. [4] [5] [1]
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The bladder wall muscle overactivity results in sporadic bladder muscle contraction, which increases pressure in the bladder and decreases the volume of urine the bladder can hold. [2] If NDO is not treated, increased pressure in the bladder can put the upper urinary tract at risk of harm, including possible permanent damage to the kidneys. [2]
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