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Cervical cancer is a type of gynecological cancer that begins from cells lining the cervix, the lower part of the uterus. [14] Cervical cancer begins when the cells that line the cervix become abnormal and grow in a pattern that is atypical for non-cancerous cells. [14] Cervical cancer is typically first identified with an abnormal pap smear. [14]
Like small-cell cancer in the lungs, the lymph nodes play a major role in spreading the cancer throughout the body. SCC begins in the inner part of the cervix and is very hard to diagnose. Due to the involvement of the lymph nodes , in its late and fatal stages, it can spread beyond the pelvic region to other organs.
Cervical cancer typically develops from precancerous changes called cervical intraepithelial neoplasia over 10 to 20 years. [3] About 90% of cervical cancer cases are squamous cell carcinomas, 10% are adenocarcinoma, and a small number are other types. [4] Diagnosis is typically by cervical screening followed by a biopsy. [2]
It is the oldest human cell line and one of the most commonly used. [1] [2] HeLa cells are durable and prolific, allowing for extensive applications in scientific study. [3] [4] The line is derived from cervical cancer cells taken on February 8, 1951, [5] from Henrietta Lacks, a 31-year-old African American mother of five, after whom the line ...
Cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is the abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer. [1] More specifically, CIN refers to the potentially precancerous transformation of cells of the cervix.
Stage 0: carcinoma in situ, abnormal cells growing in their normal place ("in situ" from Latin for "in its place"). Stage 0 can also mean no remaining cancer after preoperative treatment in some cancers (e.g. colorectal cancer). Stage I: cancers are localized to one part of the body. Stage I cancer can be surgically removed if small enough.
Results from a phase 3 clinical trial show promise for a new standard of care for treating people with advanced cervical cancer. The new treatment includes a combination of induction chemotherapy ...
Transmissible cancers follow the general pattern of cancer spread, starting with the growth of primary cancer cells at tumor sites followed by invasion of surrounding tissue and subsequent spread throughout the organism. [5] The main hurdles for surviving cells of a successful spread to a new host are histocompatibility barriers.